Sobre nós:
A peptide is a chain of amino acids linked by peptide bonds. Peptides are mainly involved in protein regulation, angiogenesis, cell proliferation, melanogenesis, cell migration, and inflammation. Bioactive peptides have been widely used in the cosmetic industry in recent decades. Peptides require low molecular weight (> 500 Da), in order to reduce the diffusion of the peptide between the epidermal layers, high stability and solubility. Over the years, the scientific community has developed a small and stable synthetic peptide fragment that activates collagen production and reduces facial wrinkles and pigmentation. Trifluoroacetyl tripeptide-2 (sequence: TFA-Val-Try-Val-OH) tripeptide synthesis, designed as a matrix metalloproteinase and elastase inhibitor. In vitro studies on the protection of ECM by trifluoro-acetyl tripeptide 2(TT2), the synthesis of proteoglycan in cell-matrix interactions, and the effect on progerin synthesis in mature human normal fibroblasts have been recently identified as a co-inducer of cellular senescence. The results suggest that trifluoroacetyl tripeptide 2 has a broader range of anti-aging properties. This reduces progerin synthesis, increases proteoglycan production, and shrinks collagen, thereby reducing wrinkles and improving tissue stiffness. In addition, its anti-wrinkling, anti-flow hanging and skin tightening effects were evaluated in two in vitro split face studies. Trifluoroacetyl tripeptide 2 has been shown to have progressive effects on wrinkles, tightness, elasticity, and sagging.
O trifluoroacetil tripépto-2 pode o envelhecimento do atraso?
Estudos mostraram que a senescência celular está intimamente relacionada à progerina. Com o envelhecimento, a presenilina se acumula cada vez mais no corpo, levando a defeitos nucleares e danos ao DNA, levando a uma variedade de envelhecimento da pele. O trifluoroacetil tripéptido-2 é um tripéptido ativo de Elafin, um derivado do inibidor da elastase. Reduz a síntese da progerina e melhora a frouxidão da pele, a flacidez e as rugas.
Mecanismo
1. Inibir a síntese da progerina para atrasar a senescência celular.
2. Promova a produção de sindecano e prolongue a vida celular.
3. Inibir a atividade das metaloproteinases da matriz MMP1, MMP3 e MMP9, reduz a quebra das proteínas da matriz extracelular e mantenha sua integridade.
4. Inibir a atividade da elastase, reduzir a degradação da elastina e tornar a pele mais apertada e elástica.
Aplicativo
É adequado para todos os tipos de anti-rugas e anti-envelhecimento, reparo firme, anti-fotão, pós-natal e pós-sol, etc. É adicionado na fase final da produção de cosméticos
Horário de postagem: 2025-07-02